Presenter(s)

Investigating the Bioactivity of Novel β-Diketonate Complexes

Abstract

Ruthenium β-diketonate complexes have emerged as promising chemotherapeutics due to their selective bioactivity against tumors. We assessed the bioactivity of novel synthesized ruthenium β-diketonate complexes on human cancer cells as well as wild-type cells. Using cell growth assays, we screened candidate ruthenium complexes and determined the IC50 value for effective candidates. Here we present a model for ruthenium-mediated growth inhibition

College

College of Science & Engineering

Department

Chemistry

Campus

Winona

First Advisor/Mentor

Jonathon Mauser

Second Advisor/Mentor

Joseph West

Location

Kryzsko Great River Ballroom, Winona, Minnesota; United States

Start Date

4-23-2026 2:00 PM

End Date

4-23-2026 3:00 PM

Presentation Type

Poster Session

Format of Presentation or Performance

In-Person

Session

2b=2pm-3pm

Poster Number

52

Included in

Chemistry Commons

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Apr 23rd, 2:00 PM Apr 23rd, 3:00 PM

Investigating the Bioactivity of Novel β-Diketonate Complexes

Kryzsko Great River Ballroom, Winona, Minnesota; United States

Ruthenium β-diketonate complexes have emerged as promising chemotherapeutics due to their selective bioactivity against tumors. We assessed the bioactivity of novel synthesized ruthenium β-diketonate complexes on human cancer cells as well as wild-type cells. Using cell growth assays, we screened candidate ruthenium complexes and determined the IC50 value for effective candidates. Here we present a model for ruthenium-mediated growth inhibition

 

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