Exploration of Existing Ebselen Pathways for the Synthesis of Ebtellur
Abstract
Ebselen is currently being assessed for a multitude of pharmaceutical uses ranging from treating bipolar disorder, acting as a preventative for heart disease/failure, as well as being a potent antiviral and antibacterial.¹ Ebselen has also been a FDA-approved candidate during the SARS-CoV-2 pandemic by inhibiting the protease responsible for viral spread. While ebselen has captured pharmaceutical interest, its tellurium analogue, ebtellur , has yet to be successfully obtained. Multiple routes to prepare ebselen have been reported, but in only one case was an attempt with analogous Te precursor reported, which was unsuccessful.
College
College of Science & Engineering
Department
Chemistry
Campus
Winona
First Advisor/Mentor
Joseph West
Start Date
4-19-2023 2:00 PM
End Date
4-19-2023 3:00 PM
Presentation Type
Poster Session
Format of Presentation or Performance
In-Person
Session
2b=2pm-3pm
Poster Number
32
Exploration of Existing Ebselen Pathways for the Synthesis of Ebtellur
Ebselen is currently being assessed for a multitude of pharmaceutical uses ranging from treating bipolar disorder, acting as a preventative for heart disease/failure, as well as being a potent antiviral and antibacterial.¹ Ebselen has also been a FDA-approved candidate during the SARS-CoV-2 pandemic by inhibiting the protease responsible for viral spread. While ebselen has captured pharmaceutical interest, its tellurium analogue, ebtellur , has yet to be successfully obtained. Multiple routes to prepare ebselen have been reported, but in only one case was an attempt with analogous Te precursor reported, which was unsuccessful.
