Exploration of New Half-Sandwich Ruthium(II) Curcuminoid Complexes
Abstract
Ruthenium complexes and curcuminoid species have both independently been shown to exhibit a number of biologically relevant properties. The complex (η6-cymene)Ru(Cl)(curcuminate) has been shown to exhibit enhanced cytotoxic properties with respect to its precursors, but no direct analogues have been reported to date. Using a straight forward method, several (cymene)Ru(Cl)("curc") have been prepared using an array of synthetic curcumin analogues.1H and13C NMR spectroscopy, mass spectrometry and single crystal X-ray diffractometry have all been utilized to characterize these compounds.
College
College of Science & Engineering
Department
Chemistry
Campus
Winona
First Advisor/Mentor
Joseph West
Second Advisor/Mentor
Valeria Stepanova (Viterbo University)
Start Date
4-19-2023 1:00 PM
End Date
4-19-2023 2:00 PM
Presentation Type
Poster Session
Format of Presentation or Performance
In-Person
Session
2a=1pm-2pm
Poster Number
7
Exploration of New Half-Sandwich Ruthium(II) Curcuminoid Complexes
Ruthenium complexes and curcuminoid species have both independently been shown to exhibit a number of biologically relevant properties. The complex (η6-cymene)Ru(Cl)(curcuminate) has been shown to exhibit enhanced cytotoxic properties with respect to its precursors, but no direct analogues have been reported to date. Using a straight forward method, several (cymene)Ru(Cl)("curc") have been prepared using an array of synthetic curcumin analogues.1H and13C NMR spectroscopy, mass spectrometry and single crystal X-ray diffractometry have all been utilized to characterize these compounds.
