Presenter(s)
Ava Dillon
Abstract
trans-4-Bromo-2-heptene (1) is a simple compound that has never been synthesized in pure form and could be a useful starting material for organic synthesis. Therefore, the goal of this research is to synthesize 1 with a multistep synthesis. The synthesis starts with the preparation of hept-2-yn-4-ol (2) via a Grignard synthesis with the triple bond acting as a masking group for the alkene. The alcohol is converted to 4-bromo-2-heptyne (3). Step 3 is the most crucial step of selectively reducing the triple bond to the desired double bond. Finally, because the reduction should produce the cis alkene, the last step is isomerization, to produce 1 (Scheme 1). Our current progress through step 2 will be reported.
College
College of Science & Engineering
Department
Chemistry
Campus
Winona
First Advisor/Mentor
Thomas Nalli
Start Date
4-24-2025 2:00 PM
End Date
4-24-2025 3:00 PM
Presentation Type
Poster Session
Format of Presentation or Performance
In-Person
Session
2b=2pm-3pm
Poster Number
12
Included in
Progress Towards the Synthesis of trans-4-Bromo-2-Heptene
trans-4-Bromo-2-heptene (1) is a simple compound that has never been synthesized in pure form and could be a useful starting material for organic synthesis. Therefore, the goal of this research is to synthesize 1 with a multistep synthesis. The synthesis starts with the preparation of hept-2-yn-4-ol (2) via a Grignard synthesis with the triple bond acting as a masking group for the alkene. The alcohol is converted to 4-bromo-2-heptyne (3). Step 3 is the most crucial step of selectively reducing the triple bond to the desired double bond. Finally, because the reduction should produce the cis alkene, the last step is isomerization, to produce 1 (Scheme 1). Our current progress through step 2 will be reported.
